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iRhom1 regulates proteasome activity via PAC1/2 under ER stress

Proteasome is a protein degradation complex that plays a major role in maintaining cellular homeostasis. Despite extensive efforts to identify protein substrates that are degraded through ubiquitination, the regulation of proteasome activity itself under diverse signals is poorly understood. In this...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lee, WonJae, Kim, YoungDoo, Park, Jisu, Shim, SangMi, Lee, Jieun, Hong, Se-hoon, Ahn, Hye-Hyun, Lee, Huikyong, Jung, Yong-Keun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4479803/
https://ncbi.nlm.nih.gov/pubmed/26109405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11559
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