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iRhom1 regulates proteasome activity via PAC1/2 under ER stress

Proteasome is a protein degradation complex that plays a major role in maintaining cellular homeostasis. Despite extensive efforts to identify protein substrates that are degraded through ubiquitination, the regulation of proteasome activity itself under diverse signals is poorly understood. In this...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Lee, WonJae, Kim, YoungDoo, Park, Jisu, Shim, SangMi, Lee, Jieun, Hong, Se-hoon, Ahn, Hye-Hyun, Lee, Huikyong, Jung, Yong-Keun
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4479803/
https://ncbi.nlm.nih.gov/pubmed/26109405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11559
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