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RAD51 135G>C substitution increases breast cancer risk in an ethnic-specific manner: a meta-analysis on 21236 cases and 19407 controls

RAD51 is a homolog of bacterial RecA protein, which plays an important role in preserving stability of the genome. RAD51 interacts with BRCA1 and BRCA2 for homologous recombination repair. A functional polymorphism (135G > C) in the RAD51 gene has been a subject of great interest, which is eviden...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sekhar, Deepa, Pooja, Singh, Kumar, Sandeep, Rajender, Singh
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4479800/
https://ncbi.nlm.nih.gov/pubmed/26108708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11588
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