Urine podocyte mRNAs mark disease activity in IgA nephropathy

BACKGROUND: Podocyte depletion is a major mechanism driving glomerulosclerosis. We and others have previously projected from model systems that podocyte-specific mRNAs in the urine pellet might serve as glomerular disease markers. We evaluated IgA nephropathy (IgAN) to test this concept. METHODS: Fr...

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Vydáno v:Nephrol Dial Transplant
Hlavní autoři: Fukuda, Akihiro, Sato, Yuji, Iwakiri, Takashi, Komatsu, Hiroyuki, Kikuchi, Masao, Kitamura, Kazuo, Wiggins, Roger C., Fujimoto, Shouichi
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
Témata:
CLINICAL SCIENCE
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4479668/
https://ncbi.nlm.nih.gov/pubmed/25956757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfv104
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