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Torin 1 partially corrects vigabatrin-induced mitochondrial increase in mouse
Recent findings in mice with targeted deletion of the GABA-metabolic enzyme succinic semialdehyde dehydrogenase revealed a new role for supraphysiological GABA (4-aminobutyric acid) in the activation of the mechanistic target of rapamycin (mTOR) that results in disruption of endogenous mitophagy. Em...
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Publicado no: | Ann Clin Transl Neurol |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
John Wiley & Sons, Ltd
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4479529/ https://ncbi.nlm.nih.gov/pubmed/26125044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.200 |
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