Expanded CD8 T-cell sharing between periphery and CNS in multiple sclerosis

OBJECTIVE: In multiple sclerosis (MS), central nervous system (CNS), cerebrospinal fluid (CSF), and blood display TCR clonal expansions of CD8(+) T cells. These clones have been assumed – but never demonstrated – to be similar in the three compartments. Addressing this key question is essential to i...

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Detalhes bibliográficos
Publicado no:Ann Clin Transl Neurol
Main Authors: Salou, Marion, Garcia, Alexandra, Michel, Laure, Gainche-Salmon, Anne, Loussouarn, Delphine, Nicol, Bryan, Guillot, Flora, Hulin, Philippe, Nedellec, Steven, Baron, Daniel, Ramstein, Gérard, Soulillou, Jean-Paul, Brouard, Sophie, Nicot, Arnaud B, Degauque, Nicolas, Laplaud, David A
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4479522/
https://ncbi.nlm.nih.gov/pubmed/26125037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.199
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