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Prediction of complex human diseases from pathway-focused candidate markers by joint estimation of marker effects: case of chronic fatigue syndrome
BACKGROUND: The current practice of using only a few strongly associated genetic markers in regression models results in generally low power in prediction or accounting for heritability of complex human traits. PURPOSE: We illustrate here a Bayesian joint estimation of single nucleotide polymorphism...
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| Publicado no: | Hum Genomics |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4479222/ https://ncbi.nlm.nih.gov/pubmed/26063326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40246-015-0030-6 |
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