The RNA-binding protein HuR (Elavl1) is essential for the B cell antibody response

Post-transcriptional regulation of mRNA by the RNA binding protein HuR (Elavl1) is required in B cells for the germinal centre reaction and for the production of class-switched antibodies in response to T-independent antigens. Transcriptome-wide examination of RNA isoforms, abundance and translation...

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Detalhes bibliográficos
Publicado no:Nat Immunol
Main Authors: Diaz-Muñoz, Manuel D., Bell, Sarah E., Fairfax, Kirsten, Monzon-Casanova, Elisa, Cunningham, Adam F., Gonzalez-Porta, Mar, Andrews, Simon R., Bunik, Victoria I., Zarnack, Kathi, Curk, Tomaž, Heggermont, Ward A., Heymans, Stephane, Gibson, Gary E., Kontoyiannis, Dimitris L., Ule, Jernej, Turner, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4479220/
https://ncbi.nlm.nih.gov/pubmed/25706746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3115
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