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The role of Rab5a GTPase in endocytosis and post-endocytic trafficking of the hCG-human luteinizing hormone receptor complex

This study examined the role of Rab5a GTPase in regulating hCG-induced internalization and trafficking of the hCG-LH receptor complex in transfected 293T cells. Coexpression of wild-type Rab5a (WT) or constitutively active Rab5a (Q79L) with LHR significantly increased hCG-induced LHR internalization...

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Détails bibliographiques
Publié dans:Cell Mol Life Sci
Auteurs principaux: Gulappa, Thippeswamy, Clouser, Christine L., Menon, K. M. J.
Format: Artigo
Langue:Inglês
Publié: SP Birkhäuser Verlag Basel 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4479136/
https://ncbi.nlm.nih.gov/pubmed/21104291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-010-0594-1
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