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Exposure to a youthful circulaton rejuvenates bone repair through modulation of β-catenin

The capacity for tissues to repair and regenerate diminishes with age. We sought to determine the age-dependent contribution of native mesenchymal cells and circulating factors on in vivo bone repair. Here we show that exposure to youthful circulation by heterochronic parabiosis reverses the aged fr...

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Pubblicato in:Nat Commun
Autori principali: Baht, Gurpreet S., Silkstone, David, Vi, Linda, Nadesan, Puviindran, Amani, Yasha, Whetstone, Heather, Wei, Qingxia, Alman, Benjamin A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Pub. Group 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4479006/
https://ncbi.nlm.nih.gov/pubmed/25988592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8131
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