High level of chromosomal instability in circulating tumor cells of ROS1-rearranged non-small-cell lung cancer

BACKGROUND: Genetic aberrations affecting the c-ros oncogene 1 (ROS1) tyrosine kinase gene have been reported in a small subset of patients with non-small-cell lung cancer (NSCLC). We evaluated whether ROS1-chromosomal rearrangements could be detected in circulating tumor cells (CTCs) and examined t...

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Publicado no:Ann Oncol
Main Authors: Pailler, E., Auger, N., Lindsay, C. R., Vielh, P., Islas-Morris-Hernandez, A., Borget, I., Ngo-Camus, M., Planchard, D., Soria, J.-C., Besse, B., Farace, F.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4478971/
https://ncbi.nlm.nih.gov/pubmed/25846554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdv165
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