Tethering human immunodeficiency virus 1 integrase to a DNA site directs integration to nearby sequences.
Certain retrovirus and retrotransposons display strong biases in the selection of host DNA sites for integration. To probe the possibility that simple tethering of the retroelement integrase protein to a target DNA site is sufficient to direct integration, the activities of a hybrid composed of huma...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1994
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44786/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7937746/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.20.9233 |
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