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Neural crest-specific TSC1 deletion in mice leads to sclerotic craniofacial bone lesion()

Tuberous sclerosis complex (TSC) is an autosomal dominant disorder caused by mutations in either TSC1 or TSC2. TSC has high frequency of osseous manifestations such as sclerotic lesions in the craniofacial region. However, an animal model that replicates TSC craniofacial bone lesions has not yet bee...

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Detalhes bibliográficos
Publicado no:J Bone Miner Res
Main Authors: Fang, Fang, Sun, Shaogang, Wang, Li, Guan, Jun-Lin, Giovannini, Marco, Zhu, Yuan, Liu, Fei
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4478231/
https://ncbi.nlm.nih.gov/pubmed/25639352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2447
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