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Mechanical Stress Promotes Maturation of Human Myocardium from Pluripotent Stem Cell-Derived Progenitors

Recent advances in pluripotent stem cell biology and directed differentiation have identified a population of human cardiovascular progenitors that give rise to cardiomyocytes, smooth muscle and endothelial cells. Because the heart develops from progenitors in 3-D under constant mechanical load, we...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Ruan, Jia-Ling, Tulloch, Nathaniel L., Saiget, Mark, Paige, Sharon L., Razumova, Maria V., Regnier, Michael, Tung, Kelvin Chan, Keller, Gordon, Pabon, Lil, Reinecke, Hans, Murry, Charles E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4478130/
https://ncbi.nlm.nih.gov/pubmed/25865043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2036
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