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Regulation of Insulin Receptor Trafficking by Bardet Biedl Syndrome Proteins
Insulin and its receptor are critical for the regulation of metabolic functions, but the mechanisms underlying insulin receptor (IR) trafficking to the plasma membrane are not well understood. Here, we show that Bardet Biedl Syndrome (BBS) proteins are necessary for IR localization to the cell surfa...
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| Publicado en: | PLoS Genet |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4478011/ https://ncbi.nlm.nih.gov/pubmed/26103456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005311 |
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