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Regulation of Insulin Receptor Trafficking by Bardet Biedl Syndrome Proteins
Insulin and its receptor are critical for the regulation of metabolic functions, but the mechanisms underlying insulin receptor (IR) trafficking to the plasma membrane are not well understood. Here, we show that Bardet Biedl Syndrome (BBS) proteins are necessary for IR localization to the cell surfa...
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| 出版年: | PLoS Genet |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4478011/ https://ncbi.nlm.nih.gov/pubmed/26103456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005311 |
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