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Prevalence and Clinicopathological Characteristics of HER2 and BRAF Mutation in Chinese Patients with Lung Adenocarcinoma

AIMS: To determine the prevalence and clinicopathological characteristics of BRAF V600E mutation and HER2 exon 20 insertions in Chinese lung adenocarcinoma (ADC) patients. METHODS: Given the fact that the driver mutations are mutually exclusive in lung ADCs, 204 EGFR/KRAS wild-type cases were enroll...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Shan, Ling, Qiu, Tian, Ling, Yun, Guo, Lei, Zheng, Bo, Wang, Bingning, Li, Wenbin, Li, Lin, Ying, Jianming
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4477932/
https://ncbi.nlm.nih.gov/pubmed/26102513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130447
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