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Induction of Antitumor Immunity In vivo Following Delivery of a Novel HPV-16 DNA Vaccine Encoding an E6/E7 Fusion antigen

Human papillomavirus type 16 (HPV-16) infection is associated with a majority of cervical cancers and a significant proportion of head and neck cancers. Here, we describe a novel engineered DNA vaccine that encodes a HPV-16 consensus E6/E7 fusion gene (pConE6E7) with the goal of increasing its antit...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Vaccine
Hauptverfasser: Yan, Jian, Reichenbach, Dawn K., Corbitt, Natasha, Hokey, David, Ramanathan, Mathura P., McKinney, Kibwei A., Weiner, David B., Sewell, Duane
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4477831/
https://ncbi.nlm.nih.gov/pubmed/19022315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2008.10.078
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