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Initial description of the human NLRP3 promoter

Mutations in NLRP3 (CIAS1) are identified in a continuum of related inflammatory disorders, known as cryopyrinopathies since NLRP3 codes for the protein cryopyrin. Approximately 40% of patients with classic presentation lack mutations in the coding region of NLRP3 suggesting heterogeneity or epigene...

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Foilsithe in:Genes Immun
Main Authors: Anderson, JP, Mueller, JL, Misaghi, A, Anderson, S, Sivagnanam, M, Kolodner, RD, Hoffman, HM
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4477692/
https://ncbi.nlm.nih.gov/pubmed/18719602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2008.66
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