Phase I study of dose-escalated busulfan with fludarabine and alemtuzumab as conditioning for allogeneic hematopoietic stem cell transplant: reduced clearance at high doses and occurrence of late sinusoidal obstruction syndrome/veno-occlusive disease

Disease recurrence after allogeneic hematopoietic cell transplant (alloHCT) remains common, making improvements in conditioning regimens desirable. A dose-response relationship between busulfan exposure and outcome is known. Using individual real-time monitoring of the busulfan area under the curve...

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Библиографические подробности
Опубликовано в: :Leuk Lymphoma
Главные авторы: O’DONNELL, PETER H., ARTZ, ANDREW S., UNDEVIA, SAMIR D., PAI, RISH K., CERRO, PAULA DEL, HOROWITZ, SARAH, GODLEY, LUCY A., HART, JOHN, INNOCENTI, FEDERICO, LARSON, RICHARD A., ODENIKE, OLATOYOSI M., STOCK, WENDY, VAN BESIEN, KOEN
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4477684/
https://ncbi.nlm.nih.gov/pubmed/20919852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10428194.2010.520773
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