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Human nucleolar protein Nop52 (RRP1/NNP-1) is involved in site 2 cleavage in internal transcribed spacer 1 of pre-rRNAs at early stages of ribosome biogenesis

During the early steps of ribosome biogenesis in mammals, the two ribosomal subunits 40S and 60S are produced via splitting of the large 90S pre-ribosomal particle (90S) into pre-40S and pre-60S pre-ribosomal particles (pre-40S and pre-60S). We previously proposed that replacement of fibrillarin by...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Yoshikawa, Harunori, Ishikawa, Hideaki, Izumikawa, Keiichi, Miura, Yutaka, Hayano, Toshiya, Isobe, Toshiaki, Simpson, Richard J., Takahashi, Nobuhiro
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4477673/
https://ncbi.nlm.nih.gov/pubmed/25969445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv470
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