Structural insights into catalysis and dimerization enhanced exonuclease activity of RNase J

RNase J is a conserved ribonuclease that belongs to the β-CASP family of nucleases. It possesses both endo- and exo-ribonuclease activities, which play a key role in pre-rRNA maturation and mRNA decay. Here we report high-resolution crystal structures of Deinococcus radiodurans RNase J complexed wit...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Zhao, Ye, Lu, Meihua, Zhang, Hui, Hu, Jing, Zhou, Congli, Xu, Qiang, Ul Hussain Shah, Amir Miraj, Xu, Hong, Wang, Liangyan, Hua, Yuejin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2015
Schlagworte:
Nucleic Acid Enzymes
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4477667/
https://ncbi.nlm.nih.gov/pubmed/25940620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv444
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