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A statistical framework for revealing signaling pathways perturbed by DNA variants
Much of the inter-individual variation in gene expression is triggered via perturbations of signaling networks by DNA variants. We present a novel probabilistic approach for identifying the particular pathways by which DNA variants perturb the signaling network. Our procedure, called PINE, relies on...
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| Publicat a: | Nucleic Acids Res |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4477643/ https://ncbi.nlm.nih.gov/pubmed/25765646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv203 |
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