Development of a high-resolution NGS-based HLA-typing and analysis pipeline

The human leukocyte antigen (HLA) complex contains the most polymorphic genes in the human genome. The classical HLA class I and II genes define the specificity of adaptive immune responses. Genetic variation at the HLA genes is associated with susceptibility to autoimmune and infectious diseases an...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Wittig, Michael, Anmarkrud, Jarl A., Kässens, Jan C., Koch, Simon, Forster, Michael, Ellinghaus, Eva, Hov, Johannes R., Sauer, Sascha, Schimmler, Manfred, Ziemann, Malte, Görg, Siegfried, Jacob, Frank, Karlsen, Tom H., Franke, Andre
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Methods Online
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4477639/
https://ncbi.nlm.nih.gov/pubmed/25753671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv184
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