Effect of Unblinding on Participants’ Perceptions of Risk and Confidence in a Large Double-blind Clinical Trial of Chemotherapy for Breast Cancer

IMPORTANCE: Blinding patients to treatment regimen is an important component of high quality randomized clinical trials (RCT) although concern exists about how receipt of a placebo will impact participants’ views, particularly among patients with cancer. OBJECTIVE: To determine if unblinding of rand...

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Опубликовано в: :JAMA Oncol
Главные авторы: Partridge, Ann H., Sepucha, Karen, O’Neill, Anne, Miller, Kathy D., Motley, Christine, Swaby, Ramona F., Schneider, Bryan P., Dang, Chau T., Northfelt, Donald W., Sledge, George W.
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4477538/
https://ncbi.nlm.nih.gov/pubmed/26114161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2015.0246
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