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The autotaxin-lysophosphatidic acid–lysophosphatidic acid receptor cascade: proposal of a novel potential therapeutic target for treating glioblastoma multiforme

Glioblastoma multiforme (GBM) is the most malignant tumor of the central nervous system (CNS). Its prognosis is one of the worst among all cancer types, and it is considered a fatal malignancy, incurable with conventional therapeutic strategies. As the bioactive multifunctional lipid mediator lysoph...

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Publicado en:Lipids Health Dis
Autor principal: Tabuchi, Sadaharu
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4477515/
https://ncbi.nlm.nih.gov/pubmed/26084470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12944-015-0059-5
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