Adenylyl Cyclase Type 5 Deficiency Protects Against Diet-Induced Obesity and Insulin Resistance

Adenylyl cyclase type 5 knockout (AC5KO) mice have increased longevity and share a similar phenotype with calorie-restricted wild-type (WT) mice. To determine the in vivo metabolic properties of AC5 deficiency, we compared the effects of standard diet (SD) and high-fat diet (HFD) on obesity, energy...

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Publicado en:Diabetes
Autores principales: Ho, David, Zhao, Xin, Yan, Lin, Yuan, Chujun, Zong, Haihong, Vatner, Dorothy E., Pessin, Jeffery E., Vatner, Stephen F.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Diabetes Association 2015
Materias:
Pharmacology and Therapeutics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4477357/
https://ncbi.nlm.nih.gov/pubmed/25732192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db14-0494
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