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The Basic Helix-Loop-Helix Transcription Factor NEUROG3 Is Required for Development of the Human Endocrine Pancreas

Neurogenin3 (NEUROG3) is a basic helix-loop-helix transcription factor required for development of the endocrine pancreas in mice. In contrast, humans with NEUROG3 mutations are born with endocrine pancreas function, calling into question whether NEUROG3 is required for human endocrine pancreas deve...

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Pubblicato in:Diabetes
Autori principali: McGrath, Patrick S., Watson, Carey L., Ingram, Cameron, Helmrath, Michael A., Wells, James M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4477351/
https://ncbi.nlm.nih.gov/pubmed/25650326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db14-1412
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