Exenatide Protects Against Glucose- and Lipid-Induced Endothelial Dysfunction: Evidence for Direct Vasodilation Effect of GLP-1 Receptor Agonists in Humans

GLP-1 receptor (GLP-1R) agonists may improve endothelial function (EF) via metabolic improvement and direct vascular action. The current study determined the effect of GLP-1R agonist exenatide on postprandial EF in type 2 diabetes and the mechanisms underlying GLP-1R agonist–mediated vasodilation. T...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Koska, Juraj, Sands, Michelle, Burciu, Camelia, D’Souza, Karen M., Raravikar, Kalyani, Liu, James, Truran, Seth, Franco, Daniel A., Schwartz, Eric A., Schwenke, Dawn C., D’Alessio, David, Migrino, Raymond Q., Reaven, Peter D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2015
Assuntos:
Pharmacology and Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4477348/
https://ncbi.nlm.nih.gov/pubmed/25720388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db14-0976
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