Peripheral inflammation increases seizure susceptibility via the induction of neuroinflammation and oxidative stress in the hippocampus

BACKGROUND: Neuroinflammation with activation of microglia and production of proinflammatory cytokines in the brain plays an active role in epileptic disorders. Brain oxidative stress has also been implicated in the pathogenesis of epilepsy. Damage in the hippocampus is associated with temporal lobe...

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Библиографические подробности
Опубликовано в: :J Biomed Sci
Главные авторы: Ho, Ying-Hao, Lin, Yu-Te, Wu, Chih-Wei J., Chao, Yung-Mei, Chang, Alice Y. W., Chan, Julie Y. H.
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2015
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4477313/
https://ncbi.nlm.nih.gov/pubmed/26100815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-015-0157-8
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