Protocatechuic Acid Prevents oxLDL-Induced Apoptosis by Activating JNK/Nrf2 Survival Signals in Macrophages

Protocatechuic acid (PCA), one of the main metabolites of complex polyphenols, exerts numerous biological activities including antiapoptotic, anti-inflammatory, and antiatherosclerotic effects. Oxidised LDL have atherogenic properties by damaging arterial wall cells and inducing p53-dependent apopto...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Varì, Rosaria, Scazzocchio, Beatrice, Santangelo, Carmela, Filesi, Carmelina, Galvano, Fabio, D'Archivio, Massimo, Masella, Roberta, Giovannini, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4477133/
https://ncbi.nlm.nih.gov/pubmed/26180584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/351827
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