Targeted Gold Nanoparticles Enhance Sensitization of Prostate Tumors to Megavoltage Radiation Therapy in vivo

We report potent radiosensitization of prostate cancers in vitro and in vivo using goserelin-conjugated gold nanorods. Progressive receptor-mediated internalization of conjugated nanorods over time increases the radiation interaction cross-section of cells and contributes to the effects observed in...

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Veröffentlicht in:Nanomedicine
Hauptverfasser: Wolfe, Tatiana, Chatterjee, Dev, Lee, Jihyoun, Grant, Jonathan D., Bhattarai, Shanta, Tailor, Ramesh, Goodrich, Glenn, Nicolucci, Patricia, Krishnan, Sunil
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476911/
https://ncbi.nlm.nih.gov/pubmed/25652893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2014.12.016
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