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Efflux pump-deficient mutants as a platform to search for microbes that produce antibiotics

Pseudomonas putida DOT-T1E-18 is a strain deficient in the major antibiotic efflux pump (TtgABC) that exhibits an overall increased susceptibility to a wide range of drugs when compared with the wild-type strain. We used this strain as a platform to search for microbes able to produce antibiotics th...

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Detalhes bibliográficos
Publicado no:Microb Biotechnol
Main Authors: Molina-Santiago, Carlos, Udaondo, Zulema, Daddaoua, Abdelali, Roca, Amalia, Martín, Jesús, Pérez-Victoria, Ignacio, Reyes, Fernando, Ramos, Juan-Luis
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476826/
https://ncbi.nlm.nih.gov/pubmed/26059350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1751-7915.12295
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