Involvement of microtubules in the link between cell volume and pH of acidic cellular compartments in rat and human hepatocytes.

Cell swelling is shown to induce an increase in acridine orange fluorescence intensity, an effect pointing to the alkalinization of acidic vesicles. Since autophagic hepatic proteolysis is accomplished by pH-sensitive proteinases within acidic lysosomes, this effect may contribute to the well-known...

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Hauptverfasser: Busch, G L, Schreiber, R, Dartsch, P C, Völkl, H, Vom Dahl, S, Häussinger, D, Lang, F
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1994
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC44768/
https://ncbi.nlm.nih.gov/pubmed/8090786
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