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Potent Methyl Oxidation of 5-Methyl-2′-deoxycytidine by Halogenated Quinoid Carcinogens and Hydrogen Peroxide via a Metal-independent Mechanism

Halogenated quinones are a class of carcinogenic intermediates and newly identified chlorination disinfection byproducts in drinking water. We found recently that the highly reactive and biologically important hydroxyl radical ((•)OH) can be produced by halogenated quinones and H(2)O(2) independent...

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Detalhes bibliográficos
Publicado no:Free Radic Biol Med
Main Authors: Shao, Jie, Huang, Chun-Hua, Kalyanaraman, Balaraman, Zhu, Ben-Zhan
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476646/
https://ncbi.nlm.nih.gov/pubmed/23376470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2013.01.010
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