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Preconditioning of skeletal myoblast-based engineered tissue constructs enables functional coupling to myocardium in vivo

OBJECTIVE: Skeletal myoblasts fuse to form functional syncytial myotubes as an integral part of the skeletal muscle. During this differentiation process, expression of proteins for mechanical and electrical integration is seized, which is a major drawback for the application of skeletal myoblasts in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Thorac Cardiovasc Surg
Hauptverfasser: Treskes, Philipp, Neef, Klaus, Srinivasan, Sureshkumar Perumal, Halbach, Marcel, Stamm, Christof, Cowan, Douglas, Scherner, Maximilian, Madershahian, Navid, Wittwer, Thorsten, Hescheler, Jürgen, Wahlers, Thorsten, Choi, Yeong-Hoon
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476636/
https://ncbi.nlm.nih.gov/pubmed/25439779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtcvs.2014.09.034
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