Presenilin-1 Dependent Neurogenesis Regulates Hippocampal Learning and Memory

Presenilin-1 (PS1), the catalytic core of the aspartyl protease γ-secretase, regulates adult neurogenesis. However, it is not clear whether the role of neurogenesis in hippocampal learning and memory is PS1-dependent, or whether PS1 loss of function in adult hippocampal neurogenesis can cause learni...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Bonds, Jacqueline A., Kuttner-Hirshler, Yafit, Bartolotti, Nancy, Tobin, Matthew K., Pizzi, Michael, Marr, Robert, Lazarov, Orly
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2015
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476567/
https://ncbi.nlm.nih.gov/pubmed/26098332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131266
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