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MicroC(3): an ex vivo microfluidic cis-coculture assay to test chemosensitivity and resistance of patient multiple myeloma cells

Chemosensitivity and resistance assays (CSRAs) aim to direct therapy based upon ex vivo response of patient tumor cells to chemotherapeutic drugs. However, successful CSRAs have yet to be developed. Here, we exposed primary CD138(+) multiple myeloma (MM) cells to bortezomib, a clinical proteasome in...

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Detalhes bibliográficos
Publicado no:Integr Biol (Camb)
Main Authors: Pak, Chorom, Callander, Natalie S., Young, Edmond W. K., Titz, Benjamin, Kim, KyungMann, Saha, Sandeep, Chng, Kenny, Asimakopoulos, Fotis, Beebe, David J., Miyamoto, Shigeki
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476551/
https://ncbi.nlm.nih.gov/pubmed/25998180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5ib00071h
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