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Chemopreventive n-3 fatty acids activate RXRα in colonocytes

The underlying mechanisms by which n-3 polyunsaturated fatty acids (PUFA) exert a chemopreventive effect in the colon have not been elucidated. Retinoid X receptors (RXR) are a family of nuclear receptors implicated in cancer chemoprevention. Since docosahexaenoic acid (DHA), an n-3 PUFA enriched in...

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Publié dans:Carcinogenesis
Auteurs principaux: Fan, Yang-Yi, Spencer, Thomas E., Wang, Naisyin, Moyer, Mary P., Chapkin, Robert S.
Format: Artigo
Langue:Inglês
Publié: 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476496/
https://ncbi.nlm.nih.gov/pubmed/12844485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgg110
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