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Comparative Risks of Aldehyde Constituents in Cigarette Smoke Using Transient Computational Fluid Dynamics/Physiologically Based Pharmacokinetic Models of the Rat and Human Respiratory Tracts
Computational fluid dynamics (CFD) modeling is well suited for addressing species-specific anatomy and physiology in calculating respiratory tissue exposures to inhaled materials. In this study, we overcame prior CFD model limitations to demonstrate the importance of realistic, transient breathing p...
Shranjeno v:
izdano v: | Toxicol Sci |
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Main Authors: | , , , , , , , , , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
Oxford University Press
2015
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4476461/ https://ncbi.nlm.nih.gov/pubmed/25858911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv071 |
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