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Comparative Risks of Aldehyde Constituents in Cigarette Smoke Using Transient Computational Fluid Dynamics/Physiologically Based Pharmacokinetic Models of the Rat and Human Respiratory Tracts

Computational fluid dynamics (CFD) modeling is well suited for addressing species-specific anatomy and physiology in calculating respiratory tissue exposures to inhaled materials. In this study, we overcame prior CFD model limitations to demonstrate the importance of realistic, transient breathing p...

詳細記述

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書誌詳細
出版年:Toxicol Sci
主要な著者: Corley, Richard A., Kabilan, Senthil, Kuprat, Andrew P., Carson, James P., Jacob, Richard E., Minard, Kevin R., Teeguarden, Justin G., Timchalk, Charles, Pipavath, Sudhakar, Glenny, Robb, Einstein, Daniel R.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476461/
https://ncbi.nlm.nih.gov/pubmed/25858911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv071
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