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Comparative Risks of Aldehyde Constituents in Cigarette Smoke Using Transient Computational Fluid Dynamics/Physiologically Based Pharmacokinetic Models of the Rat and Human Respiratory Tracts
Computational fluid dynamics (CFD) modeling is well suited for addressing species-specific anatomy and physiology in calculating respiratory tissue exposures to inhaled materials. In this study, we overcame prior CFD model limitations to demonstrate the importance of realistic, transient breathing p...
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出版年: | Toxicol Sci |
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主要な著者: | , , , , , , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
Oxford University Press
2015
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4476461/ https://ncbi.nlm.nih.gov/pubmed/25858911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv071 |
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