Leucine-rich repeat kinase 2 deficiency is protective in rhabdomyolysis-induced kidney injury

Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene are the most common known genetic cause of Parkinson's disease, and LRRK2 is also linked to Crohn's and Hansen's disease. LRRK2 is expressed in many organs in mammals but is particularly abundant in the kidney. We find that LR...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Boddu, Ravindra, Hull, Travis D., Bolisetty, Subhashini, Hu, Xianzhen, Moehle, Mark S., Daher, João Paulo Lima, Kamal, Ahmed Ibrahim, Joseph, Reny, George, James F., Agarwal, Anupam, Curtis, Lisa M., West, Andrew B.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476452/
https://ncbi.nlm.nih.gov/pubmed/25904107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv147
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