Latent transforming growth factor binding protein 4 regulates transforming growth factor beta receptor stability

Mutations in the gene for the latent transforming growth factor beta binding protein 4 (LTBP4) cause autosomal recessive cutis laxa type 1C. To understand the molecular disease mechanisms of this disease, we investigated the impact of LTBP4 loss on transforming growth factor beta (TGFβ) signaling. D...

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Publicado en:Hum Mol Genet
Autores principales: Su, Chi-Ting, Huang, Jenq-Wen, Chiang, Chih-Kang, Lawrence, Elizabeth C., Levine, Kara L., Dabovic, Branka, Jung, Christine, Davis, Elaine C., Madan-Khetarpal, Suneeta, Urban, Zsolt
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2015
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476448/
https://ncbi.nlm.nih.gov/pubmed/25882708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv139
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