Quantitative modeling of dose–response and drug combination based on pathway network

BACKGROUND: Quantitative description of dose–response of a drug for complex systems is essential for treatment of diseases and drug discovery. Given the growth of large-scale biological data obtained by multi-level assays, computational modeling has become an important approach to understand the mec...

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Detalhes bibliográficos
Publicado no:J Cheminform
Main Authors: Gu, Jiangyong, Zhang, Xinzhuang, Ma, Yimin, Li, Na, Luo, Fang, Cao, Liang, Wang, Zhenzhong, Yuan, Gu, Chen, Lirong, Xiao, Wei, Xu, Xiaojie
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476235/
https://ncbi.nlm.nih.gov/pubmed/26101547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13321-015-0066-6
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