Evolutionary comparison reveals that diverging CTCF sites are signatures of ancestral topological associating domains borders

Increasing evidence in the last years indicates that the vast amount of regulatory information contained in mammalian genomes is organized in precise 3D chromatin structures. However, the impact of this spatial chromatin organization on gene expression and its degree of evolutionary conservation is...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Gómez-Marín, Carlos, Tena, Juan J., Acemel, Rafael D., López-Mayorga, Macarena, Naranjo, Silvia, de la Calle-Mustienes, Elisa, Maeso, Ignacio, Beccari, Leonardo, Aneas, Ivy, Vielmas, Erika, Bovolenta, Paola, Nobrega, Marcelo A., Carvajal, Jaime, Gómez-Skarmeta, José Luis
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2015
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475986/
https://ncbi.nlm.nih.gov/pubmed/26034287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1505463112
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