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A tortoise–hare pattern seen in adapting structured and unstructured populations suggests a rugged fitness landscape in bacteria
In the context of Wright’s adaptive landscape, genetic epistasis can yield a multipeaked or “rugged” topography. In an unstructured population, a lineage with selective access to multiple peaks is expected to fix rapidly on one, which may not be the highest peak. In a spatially structured population...
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Publicado no: | Proc Natl Acad Sci U S A |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4475941/ https://ncbi.nlm.nih.gov/pubmed/25964348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1410631112 |
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