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A tortoise–hare pattern seen in adapting structured and unstructured populations suggests a rugged fitness landscape in bacteria

In the context of Wright’s adaptive landscape, genetic epistasis can yield a multipeaked or “rugged” topography. In an unstructured population, a lineage with selective access to multiple peaks is expected to fix rapidly on one, which may not be the highest peak. In a spatially structured population...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Nahum, Joshua R., Godfrey-Smith, Peter, Harding, Brittany N., Marcus, Joseph H., Carlson-Stevermer, Jared, Kerr, Benjamin
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475941/
https://ncbi.nlm.nih.gov/pubmed/25964348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1410631112
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