A carregar...

Pharmacological Induction of Human Fetal Globin Gene in Hydroxyurea-Resistant Primary Adult Erythroid Cells

Pharmacological induction of the fetal γ globin gene and the consequent formation of HbF (α(2)/γ(2)) in adult erythroid cells are one feasible therapeutic strategy for sickle cell disease (SCD) and severe β-thalassemias. Hydroxyurea (HU) is the current drug of choice for SCD, but serious side effect...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Chou, Yu-Chi, Chen, Ruei-Lin, Lai, Zheng-Sheng, Song, Jen-Shin, Chao, Yu-Sheng, Shen, Che-Kun James
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475914/
https://ncbi.nlm.nih.gov/pubmed/25986606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00035-15
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!