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Highly Active and Specific Tyrosine Ammonia-Lyases from Diverse Origins Enable Enhanced Production of Aromatic Compounds in Bacteria and Saccharomyces cerevisiae

Phenylalanine and tyrosine ammonia-lyases form cinnamic acid and p-coumaric acid, which are precursors of a wide range of aromatic compounds of biotechnological interest. Lack of highly active and specific tyrosine ammonia-lyases has previously been a limitation in metabolic engineering approaches....

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Publicado en:Appl Environ Microbiol
Main Authors: Jendresen, Christian Bille, Stahlhut, Steen Gustav, Li, Mingji, Gaspar, Paula, Siedler, Solvej, Förster, Jochen, Maury, Jérôme, Borodina, Irina, Nielsen, Alex Toftgaard
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475877/
https://ncbi.nlm.nih.gov/pubmed/25911487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00405-15
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