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Poised for action: USP18 restrains microglial activation in the white matter

Microglia are the resident macrophage population of the central nervous system (CNS) and are required for CNS development, homeostasis, and immune defense. Dysregulated microglial activity is involved in the pathogenesis of neuro-degenerative conditions and is the dominant driver of neuro-inflammato...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Takata, Kazuyuki, Ginhoux, Florent
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475394/
https://ncbi.nlm.nih.gov/pubmed/25971776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201591899
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