Association of defensin β-1 gene polymorphisms with asthma

BACKGROUND: Defensins are antimicrobial peptides that may take part in airway inflammation and hyperresponsiveness. OBJECTIVE: We characterized the genetic diversity in the defensin β-1 (DEFB1) locus and tested for an association between common genetic variants and asthma diagnosis. METHODS: To iden...

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Publicado en:J Allergy Clin Immunol
Main Authors: Levy, Hara, Raby, Benjamin A., Lake, Stephen, Tantisira, Kelan G., Kwiatkowski, David, Lazarus, Ross, Silverman, Edwin K., Richter, Brent, Klimecki, Walter T., Vercelli, Donata, Martinez, Fernando D., Weiss, Scott T.
Formato: Artigo
Idioma:Inglês
Publicado: 2005
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475026/
https://ncbi.nlm.nih.gov/pubmed/15696078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2004.11.013
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