Increased SNARE Protein-Protein Interactions in Orbitofrontal and Anterior Cingulate Cortices in Schizophrenia

BACKGROUND: Synaptic dysfunction in schizophrenia may be associated with abnormal expression or function of SNARE proteins (syntaxin, SNAP25, VAMP), forming the molecular complex underlying neurosecretion. The impact of such abnormalities on efficient SNARE heterotrimer formation is poorly understoo...

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Bibliographic Details
Published in:Biol Psychiatry
Main Authors: Ramos-Miguel, Alfredo, Beasley, Clare L., Dwork, Andrew J., Mann, J. John, Rosoklija, Gorazd, Barr, Alasdair M., Honer, William G.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4474796/
https://ncbi.nlm.nih.gov/pubmed/25662103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2014.12.012
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