A central role for spinal dorsal horn neurons that express neurokinin-1 receptors in chronic itch

We investigated roles for spinal neurons expressing the neurokinin-1 receptor (NK1R) and/or gastrin releasing peptide receptor (GRPR) in a mouse model of ovalbumin (OVA)-induced chronic atopic dermatitis (AD). Mice receiving repeated topical application of OVA exhibited atopic-like skin lesions and...

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Veröffentlicht in:Pain
Hauptverfasser: Akiyama, Tasuku, Nguyen, Tony, Curtis, Eric, Nishida, Katsuko, Devireddy, Jahnavi, Delahanty, Jeremy, Carstens, Mirela Iodi, Carstens, E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4474752/
https://ncbi.nlm.nih.gov/pubmed/25830923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000000172
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